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What causes the condition
From the Swindon Advertiser, first published Tuesday 4th Feb 2003.
A baby will have Down's Syndrome if it is born with an extra chromosome 21, or part of chromosome 21, giving 47 chromosomes instead of the usual 46.
Down's Syndrome is a genetic condition, and for the majority of people with it there is no specific reason why the mutation has occurred it is not the result of anything the parents did or did not do.
The syndrome is named after Dr John Langdon Down who first described it in 1866.
At present there is no treatment or cure for the condition but advances in genetic manipulation may eventually provide answers.
DS occurs in around one out of every 1,000 births, in both girls and boys. It can affect anyone, regardless of race or background.
It is said to be the most common cause of learning difficulties.
The extra chromosome can come from either the father's sperm or the mother's egg cells, or can occur just after conception.
Women who conceive after they are 35 appear to be particularly susceptible to having a child with DS but the age of the father does not appear to have a similar effect.
Pre-natal tests are offered to prospective parents by their GP or health centre if there is any reason for concern.
The most common test at the moment is the amniocentesis test.
A sample of the amniotic fluid, which surrounds the foetus in the woman's uterus, is assessed.
n A fundraising fashion show will be held at the Great Western Designer Outlet Village in Kemble Drive on May 9.
All proceeds will go towards the Down's Syndrome Swindon speech and language therapy group. If you would like more information or want to help raise cash for the group call chief fundraiser Jenny Brett on Swindon 344615 or email craig@freshbrook43.freeserve.co.uk
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